Senior Manager, Clinical Supply Chain Planning

Location: South San Francisco
Posted on: June 23, 2025

Job Description:

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. Lead supply chain strategy for Denali’s clinical products, including demand and supply planning, IRT strategy, and production management. Act as the primary supply chain contact, support Direct-to-Patient strategy, collaborate cross-functionally, troubleshoot issues, and communicate program status to stakeholders. Key Accountabilities/Core Job Responsibilities: Act as Supply Chain Lead for Denali’s clinical products including developing the supply chain strategy, demand and supply planning, and IRT strategy development Execute scenario plans and develop recommended production and inventory management strategies Serve as primary supply chain contact with internal and external stakeholders Support Direct-to-Patient supply chain strategy development and execution Work cross-functionally with CMC, Development, and Finance departments to support program development Proactively identify and troubleshoot issues to prevent missed timelines Communicate program status both verbally and through written documents and reports Drive continuous operational performance improvement efforts Lead supply chain business process development projects Lead direct report(s) through annual goal setting, growth planning, adherence to company policies, maintain training compliance and provide ongoing feedback on growth, development and areas of improvement. (if applicable) Qualifications/Skills: ? Bachelor’s degree in Industrial Engineering/Operations/Supply Chain or related field; MBA strongly preferred ? 5 years experience in clinical supply chain planning in the Life Sciences. ? Experience leading business process definition/improvement is strongly preferred ? Skilled in using influence management to drive project success ? Demonstrated ability to work accurately, meet timelines and handle multiple priorities ? Capable of responding flexibly to changing prioritization in a dynamic environment ? Strong interpersonal skills and ability to work with others in a positive “can do” and collaborative manner ? Strong verbal and written communication skills ? Advanced analytical capabilities with proficiency in Excel, Word, and PowerPoint ? Requires working knowledge of cGMP and regulations applicable to the FDA and comparable international regulatory agencies Salary Range: $152,000.00 to $185,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Keywords: , North Highlands , Senior Manager, Clinical Supply Chain Planning, Executive , South San Francisco, California